Kevin De Bruyne leaves the Champions League clash against Inter due to injury concerns ahead of the clash with Arsenal

Manchester City may have to contend with new injury concerns ahead of their Premier League clash with Arsenal this weekend.

The latest development in the Manchester City camp comes after Nathan Ake suffered a long-term muscle problem during the last international break and was substituted off for the Netherlands' 2-2 draw with Germany in the UEFA Nations League.

The Dutchman is not expected to take part in Manchester City's upcoming matches in all competitions, with Pep Guardiola having earmarked the October international break as a possible return date for the 29-year-old.

Ake's injury adds to Oscar Bobb's long-term problem. The Norwegian striker suffered a broken bone in his leg ahead of the opening Premier League match between Chelsea and Manchester City.

Now Pep Guardiola has a new big concern ahead of the opening match between Manchester City and Arsenal on Sunday afternoon: Kevin De Bruyne had to leave the game against Inter in the UEFA Champions League, probably due to groin problems.

Guardiola is expected to provide an update on De Bruyne's injury concerns after Manchester City's match against Inter at the Etihad Stadium on Wednesday night, before also facing the media during a press conference ahead of the Arsenal match on Friday afternoon.

This story is constantly evolving. More information to come.